BCL10 / BCL-10 Monoclonal Antibody LS-B11894 from LSBio

Product Specs
ItemBCL10 / BCL-10 Monoclonal Antibody
CompanyLSBio
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberLS-B11894
ApplicationsELISA, Flo, IHC-P, IP, WB
Conjugate/TagUnconjugated
FormatPBS, 0.09% sodium azide
PurityProtein G purified
ReactivityHuman
TargetBCL10 / BCL-10
IsotypeIgG1
Clone151
HostMouse
NCBI Full Gene NameBCL10 immune signaling adaptor
NCBI Gene AliasesCARMEN, CIPER, CLAP, IMD37, c-E10, mE10
ClonalityMonoclonal
Quantity0.05 mg

Specifications/Features

Specificity: Recognizes human B-cell lymphoma/leukaemia 10 (Bcl-10), a 31kD CARD (caspase recruitment domain) containing molecule that is involved in the regulation of apoptosis. Bcl-10 was originally identified through its direct involvement in t(1;14)(p22;q32) of mucosa-associated lymphoid tissue (MALT) lymphoma. The Bcl-10 molecule is predominantly located in the cytoplasm but expression has also been reported in the nucleus of some lymphomas. Recent reports suggest that Bcl-10 is essential for nuclear factor (NF)-kappaB activation after lymphocyte receptor antigen stimulation and for the development of mature B-cells

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